Recombinase-Mediated Cassette Exchange as a Novel Method To Study Somatic Hypermutation in Ramos Cells

Activation-induced cytidine deaminase (AID) mediates the somatic hypermutation (SHM) of immunoglobulin (Ig) variable (V) regions that is required for the generation of antibody diversity and for the affinity maturation of the antibody response against infectious agents and toxic substances. AID pref...

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Detalles Bibliográficos
Autores principales: Baughn, Linda B., Kalis, Susan L., MacCarthy, Thomas, Wei, Lirong, Fan, Manxia, Bergman, Aviv, Scharff, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190358/
https://www.ncbi.nlm.nih.gov/pubmed/21990614
http://dx.doi.org/10.1128/mBio.00186-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190358/
https://www.ncbi.nlm.nih.gov/pubmed/21990614
http://dx.doi.org/10.1128/mBio.00186-11

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