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Novel positron emission tomography radiotracers in brain tumor imaging

Although [18F] 2-fluoro-2-deoxy-D-glucose (FDG) is the most widely used radiopharmaceutical the world over, it is not the ideal tracer for brain imaging, owing to its high physiological cortical uptake and lack of specificity. This has paved the way for the introduction of several novel radiotracers...

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Detalles Bibliográficos
Autores principales: D’Souza, Maria Mathew, Sharma, Rajnish, Tripathi, Madhavi, Panwar, Puja, Jaimini, Abhinav, Mondal, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190493/
https://www.ncbi.nlm.nih.gov/pubmed/22013296
http://dx.doi.org/10.4103/0971-3026.85369
Descripción
Sumario:Although [18F] 2-fluoro-2-deoxy-D-glucose (FDG) is the most widely used radiopharmaceutical the world over, it is not the ideal tracer for brain imaging, owing to its high physiological cortical uptake and lack of specificity. This has paved the way for the introduction of several novel radiotracers, each with their own inherent strengths and limitations. We present the insights gained from the use of these radiotracers at our institution.