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Palmitoylation Targets AKAP79 Protein to Lipid Rafts and Promotes Its Regulation of Calcium-sensitive Adenylyl Cyclase Type 8

PKA anchoring proteins (AKAPs) optimize the efficiency of cAMP signaling by clustering interacting partners. Recently, AKAP79 has been reported to directly bind to adenylyl cyclase type 8 (AC8) and to regulate its responsiveness to store-operated Ca(2+) entry (SOCE). Although AKAP79 is well targeted...

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Detalles Bibliográficos
Autores principales:	Delint-Ramirez, Ilse, Willoughby, Debbie, Hammond, Gerald V. R., Ayling, Laura J., Cooper, Dermot M. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190942/ https://www.ncbi.nlm.nih.gov/pubmed/21771783 http://dx.doi.org/10.1074/jbc.M111.243899

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