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Truncation, Randomization, and Selection: GENERATION OF A REDUCED LENGTH c-Jun ANTAGONIST THAT RETAINS HIGH INTERACTION STABILITY
The DNA binding activity of the transcriptional regulator activator protein-1 shows considerable promise as a target in cancer therapy. A number of different strategies have been employed to inhibit the function of this protein with promise having been demonstrated both in vitro and in vivo. Peptide...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190987/ https://www.ncbi.nlm.nih.gov/pubmed/21697091 http://dx.doi.org/10.1074/jbc.M111.221267 |