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Cell Type-specific Target Selection by Combinatorial Binding of Smad2/3 Proteins and Hepatocyte Nuclear Factor 4α in HepG2 Cells

Specific regulation of target genes by transforming growth factor-β (TGF-β) in a given cellular context is determined in part by transcription factors and cofactors that interact with the Smad complex. In this study, we determined Smad2 and Smad3 (Smad2/3) binding regions in the promoters of known g...

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Detalles Bibliográficos
Autores principales:	Mizutani, Anna, Koinuma, Daizo, Tsutsumi, Shuichi, Kamimura, Naoko, Morikawa, Masato, Suzuki, Hiroshi I., Imamura, Takeshi, Miyazono, Kohei, Aburatani, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Gene Regulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191026/ https://www.ncbi.nlm.nih.gov/pubmed/21646355 http://dx.doi.org/10.1074/jbc.M110.217745

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