Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

A class of anti-virulence compounds, the salicylidene acylhydrazides, has been widely reported to block the function of the type three secretion system of several Gram-negative pathogens by a previously unknown mechanism. In this work we provide the first identification of bacterial proteins that ar...

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Detalles Bibliográficos
Autores principales: Wang, Dai, Zetterström, Caroline E., Gabrielsen, Mads, Beckham, Katherine S. H., Tree, Jai J., Macdonald, Sarah E., Byron, Olwyn, Mitchell, Tim J., Gally, David L., Herzyk, Pawel, Mahajan, Arvind, Uvell, Hanna, Burchmore, Richard, Smith, Brian O., Elofsson, Mikael, Roe, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191033/
https://www.ncbi.nlm.nih.gov/pubmed/21724850
http://dx.doi.org/10.1074/jbc.M111.233858

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