PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8(+) T cells

T cell receptor (TCR) down-modulation after antigen presentation is a fundamental process that regulates TCR signal transduction. Current understanding of this process is that intrinsic TCR/CD28 signal transduction leads to TCR down-modulation. Here, we show that the interaction between programmed c...

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Detalles Bibliográficos
Autores principales: Karwacz, Katarzyna, Bricogne, Christopher, MacDonald, Douglas, Arce, Frederick, Bennett, Clare L, Collins, Mary, Escors, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191120/
https://www.ncbi.nlm.nih.gov/pubmed/21739608
http://dx.doi.org/10.1002/emmm.201100165

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