Cargando…
PCBP2 Enhances the Antiviral Activity of IFN-α against HCV by Stabilizing the mRNA of STAT1 and STAT2
Interferon-α (IFN-α) is a natural choice for the treatment of hepatitis C, but half of the chronically infected individuals do not achieve sustained clearance of hepatitis C virus (HCV) during treatment with IFN-α alone. The virus can impair IFN-α signaling and cellular factors that have an effect o...
Autores principales: | Xin, Zhongshuai, Han, Wei, Zhao, Zhiqiang, Xia, Qing, Yin, Bin, Yuan, Jiangang, Peng, Xiaozhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191149/ https://www.ncbi.nlm.nih.gov/pubmed/22022391 http://dx.doi.org/10.1371/journal.pone.0025419 |
Ejemplares similares
-
PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23
por: Wang, Xiaole, et al.
Publicado: (2019) -
SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells
por: Poat, Bret, et al.
Publicado: (2010) -
Correction: SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells
por: Poat, Bret, et al.
Publicado: (2010) -
Poly(C)-binding protein 2 positively regulates interferon downstream signaling: PCBP2 enhances JAK-STAT signaling
por: Huang, Chenxiao, et al.
Publicado: (2022) -
STAT3 Regulates the Type I IFN-Mediated Antiviral Response by Interfering with the Nuclear Entry of STAT1
por: Wang, Huanru, et al.
Publicado: (2019)