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Epigenetic Control of Viral Life-Cycle by a DNA-Methylation Dependent Transcription Factor

Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner. The EBV genome undergoes a biphasic methylation cycle; i...

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Detalles Bibliográficos
Autores principales: Flower, Kirsty, Thomas, David, Heather, James, Ramasubramanyan, Sharada, Jones, Susan, Sinclair, Alison J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191170/
https://www.ncbi.nlm.nih.gov/pubmed/22022468
http://dx.doi.org/10.1371/journal.pone.0025922