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Bioluminescent Orthotopic Mouse Models of Human Localized Non-Small Cell Lung Cancer: Feasibility and Identification of Circulating Tumour Cells

BACKGROUND: Preclinical models of non-small cell lung cancer (NSCLC) require better clinical relevance to study disease mechanisms and innovative therapeutics. We sought to compare and refine bioluminescent orthotopic mouse models of human localized NSCLC. METHODS: Athymic nude mice underwent subcut...

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Detalles Bibliográficos
Autores principales:	Mordant, Pierre, Loriot, Yohann, Lahon, Benoit, Castier, Yves, Lesèche, Guy, Soria, Jean-Charles, Vozenin, Marie-Catherine, Decraene, Charles, Deutsch, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191172/ https://www.ncbi.nlm.nih.gov/pubmed/22022511 http://dx.doi.org/10.1371/journal.pone.0026073

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