Human FasL Gene Is a Target of β-Catenin/T-Cell Factor Pathway and Complex FasL Haplotypes Alter Promoter Functions

FasL expression on human immune cells and cancer cells plays important roles in immune homeostasis and in cancer development. Our previous study suggests that polymorphisms in the FasL promoter can significantly affect the gene expression in human cells. In addition to the functional FasL SNP -844C&...

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Detalles Bibliográficos
Autores principales: Wu, Jianming, Richards, Maureen H., Huang, Jinhai, Al-Harthi, Lena, Xu, Xiulong, Lin, Rui, Xie, Fenglong, Gibson, Andrew W., Edberg, Jeffrey C., Kimberly, Robert P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191176/
https://www.ncbi.nlm.nih.gov/pubmed/22022540
http://dx.doi.org/10.1371/journal.pone.0026143

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