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Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays
INTRODUCTION: The human epidermal growth factor receptor 2 (HER2) is an established biomarker for management of patients with breast cancer. While conventional testing of HER2 protein expression is based on semi-quantitative visual scoring of the immunohistochemistry (IHC) result, efforts to reduce...
Autores principales: | Laurinaviciene, Aida, Dasevicius, Darius, Ostapenko, Valerijus, Jarmalaite, Sonata, Lazutka, Juozas, Laurinavicius, Arvydas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191356/ https://www.ncbi.nlm.nih.gov/pubmed/21943197 http://dx.doi.org/10.1186/1746-1596-6-87 |
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