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Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury
BACKGROUND: Burn survivors develop long-term cognitive impairment with increased inflammation and apoptosis in the brain. Gelsolin, an actin-binding protein with capping and severing activities, plays a crucial role in the septic response. We investigated if gelsolin infusion could attenuate neural...
Autores principales: | Zhang, Qing-Hong, Chen, Qi, Kang, Jia-Rui, Liu, Chen, Dong, Ning, Zhu, Xiao-Mei, Sheng, Zhi-Yong, Yao, Yong-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191361/ https://www.ncbi.nlm.nih.gov/pubmed/21936896 http://dx.doi.org/10.1186/1742-2094-8-118 |
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