Cargando…

The NOTA study: non-operative treatment for acute appendicitis: prospective study on the efficacy and safety of antibiotic treatment (amoxicillin and clavulanic acid) in patients with right sided lower abdominal pain

BACKGROUND: Case control studies that randomly assign patients with diagnosis of acute appendicitis to either surgical or non-surgical treatment yield a relapse rate of approximately 14% at one year. It would be useful to know the relapse rate of patients who have, instead, been selected for a given...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tugnoli, Gregorio, Giorgini, Eleonora, Biscardi, Andrea, Villani, Silvia, Clemente, Nicola, Senatore, Gianluca, Filicori, Filippo, Antonacci, Nicola, Baldoni, Franco, De Werra, Carlo, Di Saverio, Salomone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Group 2011
Materias:	Gastroenterology and Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191386/ https://www.ncbi.nlm.nih.gov/pubmed/22021722 http://dx.doi.org/10.1136/bmjopen-2010-000006

Ejemplares similares

Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology APPendicitis ACuta) trial
por: Vanhatalo, Sanja, et al.
Publicado: (2019)

The prospective multiple-centre randomized controlled clinical study of high-dose amoxicillin-proton pump inhibitor dual therapy for H. pylori infection in Sichuan areas
por: Shen, Cheng, et al.
Publicado: (2022)

Prehospital delay and its associated psychosocial factors in patients presenting with acute appendicitis in a southwestern city in China: a single-centre prospective observational study
por: Li, Jian, et al.
Publicado: (2019)

Conservative treatment of adhesive small bowel obstruction in children: a systematic review
por: Lin, Lung-Huang, et al.
Publicado: (2014)

Neostigmine for the treatment of acute pancreatitis: a protocol for a systematic review and meta-analysis
por: He, Kun, et al.
Publicado: (2023)

Effectiveness and safety of metoclopramide in treatment of intractable hiccup: a protocol of systematic review and meta-analysis
por: Wang, Die, et al.
Publicado: (2022)

Eliminating hepatitis C in a rural Appalachian county: protocol for the Kentucky Viral Hepatitis Treatment Study (KeY Treat), a phase IV, single-arm, open-label trial of sofosbuvir/velpatasvir for the treatment of hepatitis C
por: Havens, Jennifer R, et al.
Publicado: (2021)

Research priorities in pernicious anaemia: James Lind Alliance Priority Setting Partnership
por: Staley, Kristina, et al.
Publicado: (2022)

Efficacy and safety of acupuncture as an adjuvant treatment for acute pancreatitis: a protocol of systematic review and meta-analysis
por: Zhang, Kai, et al.
Publicado: (2019)

Heterogeneity in pharmacological treatment and outcomes in Crohn’s disease patients in Catalonia: a population-based observational study
por: Brunet, Eduard, et al.
Publicado: (2022)

Assessment of a primary care e-support package of automated case finding, simplified treatment algorithm and decision support to increase hepatitis B treatment uptake in primary care clinics in Australia (SIMPLY-B Study): protocol for a pilot evaluation
por: Moussa, Dina, et al.
Publicado: (2023)

Non-pharmacological treatments for irritable bowel syndrome: study protocol of an umbrella review of systematic review and meta-analyses
por: Jin, Song, et al.
Publicado: (2019)

Nonalcoholic steatohepatitis diagnosis and treatment from the perspective of patients and primary care physicians: a cross-sectional survey
por: Nadolsky, Karl, et al.
Publicado: (2023)

Changes in hepatitis C burden and treatment trends in Europe during the era of direct-acting antivirals: a modelling study
por: Chen, Qiushi, et al.
Publicado: (2019)

Comparative efficacy and safety of probiotics for the treatment of irritable bowel syndrome: a systematic review and network meta-analysis protocol
por: Yang, Man, et al.
Publicado: (2019)

Clinical efficacy of adjuvant treatments for patients with resected biliary tract cancer: a systematic review and network meta-analysis
por: Chen, Ye, et al.
Publicado: (2022)

Treatment effectiveness and side effects of patients with hepatitis C in the prisons of Southern Taiwan: a real-life retrospective analysis
por: Tsai, Yu-Chi, et al.
Publicado: (2023)

ATTIRE: Albumin To prevenT Infection in chronic liveR failurE: study protocol for a single-arm feasibility trial
por: China, Louise, et al.
Publicado: (2016)

Risk of a subsequent diagnosis of inflammatory bowel disease in subjects with ophthalmic disorders associated with inflammatory bowel disease: a retrospective cohort analysis of UK primary care data
por: King, Dominic, et al.
Publicado: (2022)

Clinicopathologic characteristics, laboratory parameters, treatment protocols, and outcomes of pancreatic cancer: a retrospective cohort study of 1433 patients in China
por: Zhang, Shuisheng, et al.
Publicado: (2018)

Equal treatment efficacy of direct-acting antivirals in patients with chronic hepatitis C and hepatocellular carcinoma? A prospective cohort study
por: Huang, Chung-Feng, et al.
Publicado: (2019)

Identification of research trends concerning application of stent implantation in the treatment of pancreatic diseases by quantitative and biclustering analysis: a bibliometric analysis
por: Zhu, Xuan, et al.
Publicado: (2019)

Short-term outcomes and intermediate-term follow-up of Helicobacter pylori infection treatment for naïve patients: a retrospective observational study
por: Wang, Yujing, et al.
Publicado: (2022)

RITPBC: B-cell depleting therapy (rituximab) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial
por: Jopson, Laura, et al.
Publicado: (2015)

Study protocol for a randomised, double-blinded, placebo-controlled, clinical trial of S-ketamine for pain treatment in patients with chronic pancreatitis (RESET trial)
por: Juel, Jacob, et al.
Publicado: (2015)

Test accuracy of drug and antibody assays for predicting response to antitumour necrosis factor treatment in Crohn’s disease: a systematic review and meta-analysis
por: Freeman, Karoline, et al.
Publicado: (2017)

Multicentre, non-interventional study of the efficacy and tolerability of linaclotide in the treatment of irritable bowel syndrome with constipation in primary, secondary and tertiary centres: the Alpine study
por: Pohl, Daniel, et al.
Publicado: (2019)

Control Crohn Safe with episodic adalimumab monotherapy as first-line treatment study (CoCroS): study protocol for a randomised controlled trial
por: Janssen, Laura, et al.
Publicado: (2021)

A mixed methods feasibility study to evaluate the use of a low-intensity, nurse-delivered cognitive behavioural therapy for the treatment of irritable bowel syndrome
por: Dainty, Andrew David, et al.
Publicado: (2014)

The impact of IL-6 and IL-28B gene polymorphisms on treatment outcome of chronic hepatitis C infection among intravenous drug users in Croatia
por: Bogdanović, Zoran, et al.
Publicado: (2016)

Study protocol for a randomised double-blinded, sham-controlled, prospective, cross-over clinical trial of vagal neuromodulation for pain treatment in patients with chronic pancreatitis
por: Muthulingam, Janusiya Anajan, et al.
Publicado: (2019)

Efficacy and safety of guanabenz acetate treatment for non-alcoholic fatty liver disease: a study protocol for a randomised investigator-initiated phase IIa study
por: Iwaki, Michihiro, et al.
Publicado: (2022)

Treatment of Cervical Chlamydial Infection With Amoxicillin/Clavulanate Potassium
por: Mann, Melinda S., et al.
Publicado: (1993)

Improving the well-being of men by Evaluating and Addressing the Gastrointestinal Late Effects (EAGLE) of radical treatment for prostate cancer: study protocol for a mixed-method implementation project
por: Taylor, Sophia, et al.
Publicado: (2016)

Assessment of the effectiveness and safety of ethosuximide in the treatment of abdominal pain related to irritable bowel syndrome – IBSET: protocol of a randomised, parallel, controlled, double-blind and multicentre trial
por: Kerckhove, Nicolas, et al.
Publicado: (2017)

Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)
por: Ong, Sim Yee, et al.
Publicado: (2015)

Clinical effectiveness of pharmacy-led versus conventionally delivered antiviral treatment for hepatitis C in patients receiving opioid substitution therapy: a study protocol for a pragmatic cluster randomised trial
por: Radley, Andrew, et al.
Publicado: (2018)

Comparative efficacy and safety of anti-HGF/MET pathway agents plus chemotherapy versus chemotherapy alone as first-line treatment in advanced gastric cancer: a protocol for a systematic review and meta-analysis
por: Jiang, Zhiyuan, et al.
Publicado: (2021)

Investigating the safety and activity of the use of BTT1023 (Timolumab), in the treatment of patients with primary sclerosing cholangitis (BUTEO): A single-arm, two-stage, open-label, multi-centre, phase II clinical trial protocol
por: Arndtz, Katherine, et al.
Publicado: (2017)

Single-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial)
por: O'Toole, Saoirse, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ab8mhkgn500gdgl477r7d66ekl