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Hollow spheroids beyond the invasive margin indicate the malignant potential of colorectal cancer
OBJECTIVE: Tumour budding formed by histologically undifferentiated cancer cells beyond the border of the tumour margin is associated with lymph node metastasis. However, hollow tumour nests, a possible histologically advanced phenotype of tumour budding, have not been discussed. We examined whether...
Autores principales: | Tamura, Koichi, Yokoyama, Shozo, Ieda, Junji, Takifuji, Katsunari, Hotta, Tsukasa, Matsuda, Kenji, Oku, Yoshimasa, Watanabe, Takashi, Nasu, Toru, Kiriyama, Shigehisa, Yamamoto, Naoyuki, Nakamura, Yasushi, Shively, John E, Yamaue, Hiroki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191579/ https://www.ncbi.nlm.nih.gov/pubmed/22021784 http://dx.doi.org/10.1136/bmjopen-2011-000179 |
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