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Hollow spheroids beyond the invasive margin indicate the malignant potential of colorectal cancer

OBJECTIVE: Tumour budding formed by histologically undifferentiated cancer cells beyond the border of the tumour margin is associated with lymph node metastasis. However, hollow tumour nests, a possible histologically advanced phenotype of tumour budding, have not been discussed. We examined whether...

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Detalles Bibliográficos
Autores principales: Tamura, Koichi, Yokoyama, Shozo, Ieda, Junji, Takifuji, Katsunari, Hotta, Tsukasa, Matsuda, Kenji, Oku, Yoshimasa, Watanabe, Takashi, Nasu, Toru, Kiriyama, Shigehisa, Yamamoto, Naoyuki, Nakamura, Yasushi, Shively, John E, Yamaue, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191579/
https://www.ncbi.nlm.nih.gov/pubmed/22021784
http://dx.doi.org/10.1136/bmjopen-2011-000179

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