Cargando…
Optimal Control of the Lost to Follow Up in a Tuberculosis Model
This paper deals with the problem of optimal control for the transmission dynamics of tuberculosis (TB). A TB model that considers the existence of a new class (mainly in the African context) is considered: the lost to follow up individuals. Based on the model formulated and studied in the work of P...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191742/ https://www.ncbi.nlm.nih.gov/pubmed/22007263 http://dx.doi.org/10.1155/2011/398476 |
_version_ | 1782213685937176576 |
---|---|
author | Emvudu, Yves Demasse, Ramsès Djeudeu, Dany |
author_facet | Emvudu, Yves Demasse, Ramsès Djeudeu, Dany |
author_sort | Emvudu, Yves |
collection | PubMed |
description | This paper deals with the problem of optimal control for the transmission dynamics of tuberculosis (TB). A TB model that considers the existence of a new class (mainly in the African context) is considered: the lost to follow up individuals. Based on the model formulated and studied in the work of Plaire Tchinda Mouofo, (2009), the TB control is formulated and solved as an optimal control theory problem using the Pontryagin's maximum principle (Pontryagin et al., 1992). This control strategy indicates how the control of the lost to follow up class can considerably influence the basic reproduction ratio so as to reduce the number of lost to follow up. Numerical results show the performance of the optimization strategy. |
format | Online Article Text |
id | pubmed-3191742 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-31917422011-10-17 Optimal Control of the Lost to Follow Up in a Tuberculosis Model Emvudu, Yves Demasse, Ramsès Djeudeu, Dany Comput Math Methods Med Research Article This paper deals with the problem of optimal control for the transmission dynamics of tuberculosis (TB). A TB model that considers the existence of a new class (mainly in the African context) is considered: the lost to follow up individuals. Based on the model formulated and studied in the work of Plaire Tchinda Mouofo, (2009), the TB control is formulated and solved as an optimal control theory problem using the Pontryagin's maximum principle (Pontryagin et al., 1992). This control strategy indicates how the control of the lost to follow up class can considerably influence the basic reproduction ratio so as to reduce the number of lost to follow up. Numerical results show the performance of the optimization strategy. Hindawi Publishing Corporation 2011 2011-10-11 /pmc/articles/PMC3191742/ /pubmed/22007263 http://dx.doi.org/10.1155/2011/398476 Text en Copyright © 2011 Yves Emvudu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Emvudu, Yves Demasse, Ramsès Djeudeu, Dany Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title | Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title_full | Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title_fullStr | Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title_full_unstemmed | Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title_short | Optimal Control of the Lost to Follow Up in a Tuberculosis Model |
title_sort | optimal control of the lost to follow up in a tuberculosis model |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191742/ https://www.ncbi.nlm.nih.gov/pubmed/22007263 http://dx.doi.org/10.1155/2011/398476 |
work_keys_str_mv | AT emvuduyves optimalcontrolofthelosttofollowupinatuberculosismodel AT demasseramses optimalcontrolofthelosttofollowupinatuberculosismodel AT djeudeudany optimalcontrolofthelosttofollowupinatuberculosismodel |