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Positive selection on the Plasmodium falciparum clag2 gene encoding a component of the erythrocyte-binding rhoptry protein complex

A protein complex of high-molecular-mass proteins (PfRhopH) of the human malaria parasite Plasmodium falciparum induces host protective immunity and therefore is a candidate for vaccine development. Clarification of the level of polymorphism and the evolutionary processes is important both for vacci...

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Detalles Bibliográficos
Autores principales: Alexandre, Jean SF, Kaewthamasorn, Morakot, Yahata, Kazuhide, Nakazawa, Shusuke, Kaneko, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Tropical Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191777/
https://www.ncbi.nlm.nih.gov/pubmed/22028613
http://dx.doi.org/10.2149/tmh.2011-12