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Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria

Untreated asymptomatic bacteriuria can lead to urinary tract infection (UTI) in pregnancy with devastating maternal and neonatal effects such as prematurity and low birth weight, higher fetal mortality rates and significant maternal morbidity. We carried out a two year (April 2007 to March 2009) cro...

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Autores principales: Kehinde, Aderemi O., Adedapo, Kayode S., Aimaikhu, Christopher O., Odukogbe, Akin-tunde A., Olayemi, Oladapo, Salako, Babatunde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Tropical Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191778/
https://www.ncbi.nlm.nih.gov/pubmed/22028612
http://dx.doi.org/10.2149/tmh.2011-02
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author Kehinde, Aderemi O.
Adedapo, Kayode S.
Aimaikhu, Christopher O.
Odukogbe, Akin-tunde A.
Olayemi, Oladapo
Salako, Babatunde
author_facet Kehinde, Aderemi O.
Adedapo, Kayode S.
Aimaikhu, Christopher O.
Odukogbe, Akin-tunde A.
Olayemi, Oladapo
Salako, Babatunde
author_sort Kehinde, Aderemi O.
collection PubMed
description Untreated asymptomatic bacteriuria can lead to urinary tract infection (UTI) in pregnancy with devastating maternal and neonatal effects such as prematurity and low birth weight, higher fetal mortality rates and significant maternal morbidity. We carried out a two year (April 2007 to March 2009) cross-sectional epidemiological study to determine the prevalence of significant bacteriuria among asymptomatic antenatal clinic attendees at two antenatal clinics (ANCs) in University College Hospital and Adeoyo Maternity Hospital, both in Ibadan, Nigeria. All consenting ANC attendees without UTI were enrolled in the study. Urine specimens of 5 to 10 ml collected from each subject were examined microscopically for white blood cells, red blood cells and bacteria. The specimens were further cultured on MacConkey agar using a sterile bacteriological loop that delivered 0.002 ml of urine. Colony counts yielding bacterial growth of more than 10(5)/ml of pure isolates were considered significant. Of the 473 subjects studied, 136 had significant bacteriuria, giving a prevalence rate of 28.8%. The highest age specific prevalence (47.8%) was found in the 25–29 year olds while only one (0.7%) was found in the teenage group. A large percentage (64.0%) of subjects with significant bacteriuria had tertiary education, compared with 4.4% who had no formal education but the association was not statistically significant (X(2) = 0.47, p = 0.79). The majority (75.8%) of subjects with significant bacteriuria had no previous history of abortion, while 20 (14.7%) had one previous abortion and only three (2.1%) admitted to three previous abortions (X(2) = 5.16, p = 0.16). The majority (69.8%) of those with significant bacteriuria presented at second trimester while 38 (28.0%) presented at third trimester (X(2) = 6.5, p = 37). Only 22 (4.6%) of the studied subjects presented at first trimester, and 3 (13.7%) of these had significant bacteriuria. The prevalence of asymptomatic bacteriuria is high among this study population. Hence we suggest that advocacy programs be initiated to urge pregnant women to access ANC services early in pregnancy.
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spelling pubmed-31917782011-10-25 Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria Kehinde, Aderemi O. Adedapo, Kayode S. Aimaikhu, Christopher O. Odukogbe, Akin-tunde A. Olayemi, Oladapo Salako, Babatunde Trop Med Health Original Article Untreated asymptomatic bacteriuria can lead to urinary tract infection (UTI) in pregnancy with devastating maternal and neonatal effects such as prematurity and low birth weight, higher fetal mortality rates and significant maternal morbidity. We carried out a two year (April 2007 to March 2009) cross-sectional epidemiological study to determine the prevalence of significant bacteriuria among asymptomatic antenatal clinic attendees at two antenatal clinics (ANCs) in University College Hospital and Adeoyo Maternity Hospital, both in Ibadan, Nigeria. All consenting ANC attendees without UTI were enrolled in the study. Urine specimens of 5 to 10 ml collected from each subject were examined microscopically for white blood cells, red blood cells and bacteria. The specimens were further cultured on MacConkey agar using a sterile bacteriological loop that delivered 0.002 ml of urine. Colony counts yielding bacterial growth of more than 10(5)/ml of pure isolates were considered significant. Of the 473 subjects studied, 136 had significant bacteriuria, giving a prevalence rate of 28.8%. The highest age specific prevalence (47.8%) was found in the 25–29 year olds while only one (0.7%) was found in the teenage group. A large percentage (64.0%) of subjects with significant bacteriuria had tertiary education, compared with 4.4% who had no formal education but the association was not statistically significant (X(2) = 0.47, p = 0.79). The majority (75.8%) of subjects with significant bacteriuria had no previous history of abortion, while 20 (14.7%) had one previous abortion and only three (2.1%) admitted to three previous abortions (X(2) = 5.16, p = 0.16). The majority (69.8%) of those with significant bacteriuria presented at second trimester while 38 (28.0%) presented at third trimester (X(2) = 6.5, p = 37). Only 22 (4.6%) of the studied subjects presented at first trimester, and 3 (13.7%) of these had significant bacteriuria. The prevalence of asymptomatic bacteriuria is high among this study population. Hence we suggest that advocacy programs be initiated to urge pregnant women to access ANC services early in pregnancy. The Japanese Society of Tropical Medicine 2011-09 2011-09-30 /pmc/articles/PMC3191778/ /pubmed/22028612 http://dx.doi.org/10.2149/tmh.2011-02 Text en © 2011 Japanese Society of Tropical Medicine This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kehinde, Aderemi O.
Adedapo, Kayode S.
Aimaikhu, Christopher O.
Odukogbe, Akin-tunde A.
Olayemi, Oladapo
Salako, Babatunde
Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title_full Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title_fullStr Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title_full_unstemmed Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title_short Significant Bacteriuria Among Asymptomatic Antenatal Clinic Attendees In Ibadan, Nigeria
title_sort significant bacteriuria among asymptomatic antenatal clinic attendees in ibadan, nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191778/
https://www.ncbi.nlm.nih.gov/pubmed/22028612
http://dx.doi.org/10.2149/tmh.2011-02
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