Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (TLR4)

BACKGROUND: Differences in responses to bacterial surface lipopolysaccharides (LPSs) are apparent between and within mammalian species. It has been shown in mice that resistance to LPS is caused by defects in the Toll-like receptor 4 gene (Tlr4), the product of which is thought to bind LPS and media...

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Detalles Bibliográficos
Autores principales: Smirnova, Irina, Poltorak, Alexander, Chan, Edward KL, McBride, Colleen, Beutler, Bruce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31919/
https://www.ncbi.nlm.nih.gov/pubmed/11104518

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