Elucidation of the Glucose Transport Pathway in Glucose Transporter 4 via Steered Molecular Dynamics Simulations

BACKGROUND: GLUT4 is a predominant insulin regulated glucose transporter expressed in major glucose disposal tissues such as adipocytes and muscles. Under the unstimulated state, GLUT4 resides within intracellular vesicles. Various stimuli such as insulin translocate this protein to the plasma membr...

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Detalles Bibliográficos
Autores principales: Sheena, Aswathy, Mohan, Suma S., Haridas, Nidhina Pachakkil A., Anilkumar, Gopalakrishnapillai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192114/
https://www.ncbi.nlm.nih.gov/pubmed/22022441
http://dx.doi.org/10.1371/journal.pone.0025747

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