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A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection
Staphylococcus aureus is a major cause of human disease, responsible for half a million infections and approximately 20,000 deaths per year in the United States alone (1,2). This pathogen secretes α-hemolysin, a pore-forming cytotoxin that contributes to the pathogenesis of pneumonia (3–5). α-hemoly...
Autores principales: | Inoshima, Ichiro, Inoshima, Naoko, Wilke, Georgia, Powers, Michael, Frank, Karen, Wang, Yang, Wardenburg, Juliane Bubeck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192248/ https://www.ncbi.nlm.nih.gov/pubmed/21926978 http://dx.doi.org/10.1038/nm.2451 |
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