Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts

Cellular senescence can be induced by a variety of mechanisms, and recent data suggest a key role for cytokine networks to maintain the senescent state. Here, we have used a proteomic LC-MS/MS approach to identify new extracellular regulators of senescence in human fibroblasts. We identified 26 extr...

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Detalles Bibliográficos
Autores principales: Micutkova, Lucia, Diener, Thomas, Li, Chen, Rogowska-Wrzesinska, Adelina, Mueck, Christoph, Huetter, Eveline, Weinberger, Birgit, Grubeck-Loebenstein, Beatrix, Roepstorff, Peter, Zeng, Rong, Jansen-Duerr, Pidder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192261/
https://www.ncbi.nlm.nih.gov/pubmed/21820463
http://dx.doi.org/10.1016/j.mad.2011.07.005

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