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Matrix-embedded cells control osteoclast formation
Osteoclasts resorb the mineralized matrices formed by chondrocytes or osteoblasts. The cytokine receptor activator of NFκB ligand (RANKL) is essential for osteoclast formation and thought to be supplied by osteoblasts or their precursors. However, RANKL is expressed by a variety of cell types and it...
Autores principales: | Xiong, Jinhu, Onal, Melda, Jilka, Robert L., Weinstein, Robert S., Manolagas, Stavros C., O’Brien, Charles A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192296/ https://www.ncbi.nlm.nih.gov/pubmed/21909103 http://dx.doi.org/10.1038/nm.2448 |
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