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Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3

Infantile Krabbe disease results in the accumulation of lipid-raft-associated galactosylsphingosine (psychosine), demyelination, neurodegeneration and premature death. Recently, axonopathy has been depicted as a contributing factor in the progression of neurodegeneration in the Twitcher mouse, a bon...

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Detalles Bibliográficos
Autores principales: Smith, Benjamin, Galbiati, Francesca, Cantuti Castelvetri, Ludovico, Givogri, Maria I, Lopez-Rosas, Aurora, Bongarzone, Ernesto R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192484/
https://www.ncbi.nlm.nih.gov/pubmed/21929508
http://dx.doi.org/10.1042/AN20110019