Toll-like receptor 2 contributes to chemokine gene expression and macrophage infiltration in the dorsal root ganglia after peripheral nerve injury

BACKGROUND: We have previously reported that nerve injury-induced neuropathic pain is attenuated in toll-like receptor 2 (TLR2) knock-out mice. In these mice, inflammatory gene expression and spinal cord microglia actvation is compromised, whereas the effects in the dorsal root ganglia (DRG) have no...

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Detalles Bibliográficos
Autores principales: Kim, Donghoon, You, Byunghyun, Lim, Hyoungsub, Lee, Sung Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192680/
https://www.ncbi.nlm.nih.gov/pubmed/21951975
http://dx.doi.org/10.1186/1744-8069-7-74

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