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A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes
BACKGROUND: Reports of severe cases and increasing levels of drug resistance highlight the importance of improved Plasmodium vivax case management. Whereas monitoring P. vivax resistance to anti-malarial drug by in vivo and in vitro tests remain challenging, molecular markers of resistance represent...
Autores principales: | Barnadas, Céline, Kent, David, Timinao, Lincoln, Iga, Jonah, Gray, Laurie R, Siba, Peter, Mueller, Ivo, Thomas, Peter J, Zimmerman, Peter A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192712/ https://www.ncbi.nlm.nih.gov/pubmed/21943242 http://dx.doi.org/10.1186/1475-2875-10-282 |
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