The effect of murine cytomegalovirus IE-3 specific shRNA is dependent on intragenic target site due to multiple transcription initiation sites

BACKGROUND: Murine cytomegalovirus (MCMV) is closely related to human cytomegalovirus (HCMV) which is responsible for a variety of diseases, including retinitis, in immunocompromised individuals. Small inhibitory RNA molecules directed against essential viral regulatory genes may prove clinically us...

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Detalles Bibliográficos
Autores principales: Marshall, Brendan, Zhang, Ming, Atherton, Sally S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192721/
https://www.ncbi.nlm.nih.gov/pubmed/21923934
http://dx.doi.org/10.1186/2042-4280-2-9

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