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Transmission Selects for HIV-1 Strains of Intermediate Virulence: A Modelling Approach
Recent data shows that HIV-1 is characterised by variation in viral virulence factors that is heritable between infections, which suggests that viral virulence can be naturally selected at the population level. A trade-off between transmissibility and duration of infection appears to favour viruses...
Autores principales: | Shirreff, George, Pellis, Lorenzo, Laeyendecker, Oliver, Fraser, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192807/ https://www.ncbi.nlm.nih.gov/pubmed/22022243 http://dx.doi.org/10.1371/journal.pcbi.1002185 |
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