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The Dynamics of Supply and Demand in mRNA Translation
We study the elongation stage of mRNA translation in eukaryotes and find that, in contrast to the assumptions of previous models, both the supply and the demand for tRNA resources are important for determining elongation rates. We find that increasing the initiation rate of translation can lead to t...
Autores principales: | Brackley, Chris A., Romano, M. Carmen, Thiel, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192816/ https://www.ncbi.nlm.nih.gov/pubmed/22022250 http://dx.doi.org/10.1371/journal.pcbi.1002203 |
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