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Three Structure-Selective Endonucleases Are Essential in the Absence of BLM Helicase in Drosophila

DNA repair mechanisms in mitotically proliferating cells avoid generating crossovers, which can contribute to genome instability. Most models for the production of crossovers involve an intermediate with one or more four-stranded Holliday junctions (HJs), which are resolved into duplex molecules thr...

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Detalles Bibliográficos
Autores principales: Andersen, Sabrina L., Kuo, H. Kenny, Savukoski, Daniel, Brodsky, Michael H., Sekelsky, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192830/
https://www.ncbi.nlm.nih.gov/pubmed/22022278
http://dx.doi.org/10.1371/journal.pgen.1002315

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