A Novel Core Genome-Encoded Superantigen Contributes to Lethality of Community-Associated MRSA Necrotizing Pneumonia

Bacterial superantigens (SAg) stimulate T-cell hyper-activation resulting in immune modulation and severe systemic illnesses such as Staphylococcus aureus toxic shock syndrome. However, all known S. aureus SAgs are encoded by mobile genetic elements and are made by only a proportion of strains. Here...

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Detalles Bibliográficos
Autores principales: Wilson, Gillian J., Seo, Keun Seok, Cartwright, Robyn A., Connelley, Timothy, Chuang-Smith, Olivia N., Merriman, Joseph A., Guinane, Caitriona M., Park, Joo Youn, Bohach, Gregory A., Schlievert, Patrick M., Morrison, W. Ivan, Fitzgerald, J. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192841/
https://www.ncbi.nlm.nih.gov/pubmed/22022262
http://dx.doi.org/10.1371/journal.ppat.1002271

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