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A Viral Nuclear Noncoding RNA Binds Re-localized Poly(A) Binding Protein and Is Required for Late KSHV Gene Expression

During the lytic phase of infection, the gamma herpesvirus Kaposi's Sarcoma-Associated Herpesvirus (KSHV) expresses a highly abundant, 1.1 kb nuclear noncoding RNA of unknown function. We observe that this polyadenylated nuclear (PAN) RNA avidly binds host poly(A)-binding protein C1 (PABPC1), w...

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Detalles Bibliográficos
Autores principales:	Borah, Sumit, Darricarrère, Nicole, Darnell, Alicia, Myoung, Jinjong, Steitz, Joan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192849/ https://www.ncbi.nlm.nih.gov/pubmed/22022268 http://dx.doi.org/10.1371/journal.ppat.1002300

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