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DNA stretching by bacterial initiators promotes replication origin melting

Many replication initiators form higher-order oligomers that process host origins to promote replisome formation. In addition to dedicated duplex DNA-binding domains, cellular initiators possess AAA+ (ATPases Associated with various cellular Activities) elements that drive functions ranging from pro...

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Detalles Bibliográficos
Autores principales: Duderstadt, Karl E., Chuang, Kevin, Berger, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192921/
https://www.ncbi.nlm.nih.gov/pubmed/21964332
http://dx.doi.org/10.1038/nature10455