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Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus
The Hedgehog (Hh) family of secreted proteins is essential for development in both vertebrates and invertebrates. As one of main morphogens during metazoan development, the graded Hh signal is transduced across the plasma membrane by Smoothened (Smo) through the differential phosphorylation of its c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193457/ https://www.ncbi.nlm.nih.gov/pubmed/21844892 http://dx.doi.org/10.1038/cr.2011.136 |