Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development

Methylation of cytosine is a DNA modification associated with gene repression. Recently, a novel cytosine modification, 5-hydroxymethylcytosine (5-hmC) has been discovered. Here we examine 5-hmC distribution during mammalian development and in cellular systems, and show that the developmental dynami...

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Detalles Bibliográficos
Autores principales: Ruzov, Alexey, Tsenkina, Yanina, Serio, Andrea, Dudnakova, Tatiana, Fletcher, Judy, Bai, Yu, Chebotareva, Tatiana, Pells, Steve, Hannoun, Zara, Sullivan, Gareth, Chandran, Siddharthan, Hay, David C, Bradley, Mark, Wilmut, Ian, De Sousa, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193467/
https://www.ncbi.nlm.nih.gov/pubmed/21747414
http://dx.doi.org/10.1038/cr.2011.113

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