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Over-expression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor null mice

The vitamin D receptor (VDR) ligand, 1,25(OH)(2)D(3), reduces proliferation and enhances differentiation and thus has been investigated for a role in preventing or treating cancer. Mice deficient for the VDR display a hyperproliferative response in the hair follicle and epidermis and decreased epide...

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Detalles Bibliográficos
Autores principales: Teichert, Arnaud, Elalieh, Hashem, Elias, Peter, Welsh, JoEllen, Bikle, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193543/
https://www.ncbi.nlm.nih.gov/pubmed/21814234
http://dx.doi.org/10.1038/jid.2011.196