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Over-expression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor null mice
The vitamin D receptor (VDR) ligand, 1,25(OH)(2)D(3), reduces proliferation and enhances differentiation and thus has been investigated for a role in preventing or treating cancer. Mice deficient for the VDR display a hyperproliferative response in the hair follicle and epidermis and decreased epide...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193543/ https://www.ncbi.nlm.nih.gov/pubmed/21814234 http://dx.doi.org/10.1038/jid.2011.196 |