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Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model
BACKGROUND: A genetic knock-in mouse model expressing the R192Q mutation of the α1-subunit of the Ca(V)2.1 channels frequently found in patients with familial hemiplegic migraine shows functional upregulation of ATP-sensitive P2X3 receptors of trigeminal sensory neurons that transduce nociceptive in...
Autores principales: | Gnanasekaran, Aswini, Sundukova, Mayya, van den Maagdenberg, Arn MJM, Fabbretti, Elsa, Nistri, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193817/ https://www.ncbi.nlm.nih.gov/pubmed/21958474 http://dx.doi.org/10.1186/1744-8069-7-77 |
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