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Characterization of pathogenic germline mutations in human Protein Kinases

BACKGROUND: Protein Kinases are a superfamily of proteins involved in crucial cellular processes such as cell cycle regulation and signal transduction. Accordingly, they play an important role in cancer biology. To contribute to the study of the relation between kinases and disease we compared patho...

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Detalles Bibliográficos
Autores principales:	Izarzugaza, Jose MG, Hopcroft, Lisa EM, Baresic, Anja, Orengo, Christine A, Martin, Andrew CR, Valencia, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194193/ https://www.ncbi.nlm.nih.gov/pubmed/21992016 http://dx.doi.org/10.1186/1471-2105-12-S4-S1

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