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Prevention of siderophore- mediated gut-derived sepsis due to P. aeruginosa can be achieved without iron provision by maintaining local phosphate abundance: role of pH
BACKGROUND: During extreme physiological stress, the intestinal tract can be transformed into a harsh environment characterized by regio- spatial alterations in oxygen, pH, and phosphate concentration. When the human intestine is exposed to extreme medical interventions, the normal flora becomes rep...
Autores principales: | Romanowski, Kathleen, Zaborin, Alexander, Fernandez, Hoylan, Poroyko, Valeriy, Valuckaite, Vesta, Gerdes, Svetlana, Liu, Donald C, Zaborina, Olga Y, Alverdy, John C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195088/ https://www.ncbi.nlm.nih.gov/pubmed/21943078 http://dx.doi.org/10.1186/1471-2180-11-212 |
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