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Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade
The inhibitory receptor programmed death-1 (PD-1) and its ligand, programmed death-ligand 1 (PD-L1) are involved in immune evasion mechanisms for several pathogens causing chronic infections. Blockade of the PD-1/PD-L1 pathway restores anti-virus immune responses, with concomitant reduction in viral...
Autores principales: | Ikebuchi, Ryoyo, Konnai, Satoru, Shirai, Tatsuya, Sunden, Yuji, Murata, Shiro, Onuma, Misao, Ohashi, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195098/ https://www.ncbi.nlm.nih.gov/pubmed/21943148 http://dx.doi.org/10.1186/1297-9716-42-103 |
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