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Dll4-Notch signaling as a therapeutic target in tumor angiogenesis
Tumor angiogenesis is an important target for cancer therapy, with most current therapies designed to block the VEGF signaling pathway. However, clinical resistance to anti-VEGF therapy highlights the need for targeting additional tumor angiogenesis signaling pathways. The endothelial Notch ligand D...
Autores principales: | Kuhnert, Frank, Kirshner, Jessica R, Thurston, Gavin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195111/ https://www.ncbi.nlm.nih.gov/pubmed/21923938 http://dx.doi.org/10.1186/2045-824X-3-20 |
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