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Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature

A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care t...

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Detalles Bibliográficos
Autores principales: Babu, Thirunavukkarasu Arun, Sharmila, Vijayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195142/
https://www.ncbi.nlm.nih.gov/pubmed/22022015
http://dx.doi.org/10.4103/0253-7613.84987
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author Babu, Thirunavukkarasu Arun
Sharmila, Vijayan
author_facet Babu, Thirunavukkarasu Arun
Sharmila, Vijayan
author_sort Babu, Thirunavukkarasu Arun
collection PubMed
description A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care to general ward for completion of antibiotic course. One day prior to the planned discharge, child suddenly developed poor sensorium, flaccidity, apnea, and cyanosis within seconds of receiving intravenous cefotaxime and was found to have bradypnea with bradycardia. Prompt resuscitation was carried out with artificial ventilation, adrenaline, and steroids. Spontaneous breathing reappeared and the clinical condition improved.
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spelling pubmed-31951422011-10-21 Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature Babu, Thirunavukkarasu Arun Sharmila, Vijayan Indian J Pharmacol Drug Watch A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care to general ward for completion of antibiotic course. One day prior to the planned discharge, child suddenly developed poor sensorium, flaccidity, apnea, and cyanosis within seconds of receiving intravenous cefotaxime and was found to have bradypnea with bradycardia. Prompt resuscitation was carried out with artificial ventilation, adrenaline, and steroids. Spontaneous breathing reappeared and the clinical condition improved. Medknow Publications 2011 /pmc/articles/PMC3195142/ /pubmed/22022015 http://dx.doi.org/10.4103/0253-7613.84987 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Drug Watch
Babu, Thirunavukkarasu Arun
Sharmila, Vijayan
Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title_full Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title_fullStr Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title_full_unstemmed Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title_short Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
title_sort cefotaxime-induced near-fatal anaphylaxis in a neonate: a case report and review of literature
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195142/
https://www.ncbi.nlm.nih.gov/pubmed/22022015
http://dx.doi.org/10.4103/0253-7613.84987
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