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Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature
A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195142/ https://www.ncbi.nlm.nih.gov/pubmed/22022015 http://dx.doi.org/10.4103/0253-7613.84987 |
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author | Babu, Thirunavukkarasu Arun Sharmila, Vijayan |
author_facet | Babu, Thirunavukkarasu Arun Sharmila, Vijayan |
author_sort | Babu, Thirunavukkarasu Arun |
collection | PubMed |
description | A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care to general ward for completion of antibiotic course. One day prior to the planned discharge, child suddenly developed poor sensorium, flaccidity, apnea, and cyanosis within seconds of receiving intravenous cefotaxime and was found to have bradypnea with bradycardia. Prompt resuscitation was carried out with artificial ventilation, adrenaline, and steroids. Spontaneous breathing reappeared and the clinical condition improved. |
format | Online Article Text |
id | pubmed-3195142 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-31951422011-10-21 Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature Babu, Thirunavukkarasu Arun Sharmila, Vijayan Indian J Pharmacol Drug Watch A case of 7-day-old male neonate with cefotaxime-induced near-fatal anaphylaxis is being reported. Child was started on intravenous cefotaxime on day 3 of life in view of early-onset sepsis with pneumonia, following which there was clinical improvement. Child was then shifted out of intensive care to general ward for completion of antibiotic course. One day prior to the planned discharge, child suddenly developed poor sensorium, flaccidity, apnea, and cyanosis within seconds of receiving intravenous cefotaxime and was found to have bradypnea with bradycardia. Prompt resuscitation was carried out with artificial ventilation, adrenaline, and steroids. Spontaneous breathing reappeared and the clinical condition improved. Medknow Publications 2011 /pmc/articles/PMC3195142/ /pubmed/22022015 http://dx.doi.org/10.4103/0253-7613.84987 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Drug Watch Babu, Thirunavukkarasu Arun Sharmila, Vijayan Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title | Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title_full | Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title_fullStr | Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title_full_unstemmed | Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title_short | Cefotaxime-induced near-fatal anaphylaxis in a neonate: A case report and review of literature |
title_sort | cefotaxime-induced near-fatal anaphylaxis in a neonate: a case report and review of literature |
topic | Drug Watch |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195142/ https://www.ncbi.nlm.nih.gov/pubmed/22022015 http://dx.doi.org/10.4103/0253-7613.84987 |
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