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The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes

BACKGROUND: The Anaphase Promoting Complex or Cyclosome (APC/C) is the largest member of the ubiquitin ligase [E3] family. It plays a crucial role in the control of the cell cycle and cell proliferation by mediating the proteolysis of key components by the proteasome. APC/C is made of a dozen subuni...

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Detalles Bibliográficos
Autores principales:	Eme, Laura, Trilles, Aurélie, Moreira, David, Brochier-Armanet, Céline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195147/ https://www.ncbi.nlm.nih.gov/pubmed/21943402 http://dx.doi.org/10.1186/1471-2148-11-265

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