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Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8(+) Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)
Indoleamine 2,3-dioxygenase (IDO) catalyzes the initial and rate-limiting step of tryptophan catabolism in a specific pathway, resulting in a series of extracellular messengers collectively known as kynurenines. IDO has been recognized as an authentic regulator of immunity not only in mammalian preg...
Autores principales: | Pallotta, Maria T., Orabona, Ciriana, Volpi, Claudia, Grohmann, Ursula, Puccetti, Paolo, Fallarino, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195250/ https://www.ncbi.nlm.nih.gov/pubmed/22084591 |
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