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RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy

Cutaneous malignant melanoma is one of the most serious skin cancers and is highly invasive and markedly resistant to conventional therapy. Melanomagenesis is initially triggered by environmental agents including ultraviolet (UV), which induces genetic/epigenetic alterations in the chromosomes of me...

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Detalles Bibliográficos
Autores principales:	Yajima, Ichiro, Kumasaka, Mayuko Y., Thang, Nguyen Dinh, Goto, Yuji, Takeda, Kozue, Yamanoshita, Osamu, Iida, Machiko, Ohgami, Nobutaka, Tamura, Haruka, Kawamoto, Yoshiyuki, Kato, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195305/ https://www.ncbi.nlm.nih.gov/pubmed/22013435 http://dx.doi.org/10.1155/2012/354191

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