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Divergent effect of mammalian PLCζ in generating Ca(2+) oscillations in somatic cells compared with eggs
Sperm PLCζ (phospholipase Cζ) is a distinct phosphoinositide-specific PLC isoform that is proposed to be the physiological trigger of egg activation and embryo development at mammalian fertilization. Recombinant PLCζ has the ability to trigger Ca(2+) oscillations when expressed in eggs, but it is no...
Autores principales: | Phillips, Sally V., Yu, Yuansong, Rossbach, Andreas, Nomikos, Michail, Vassilakopoulou, Vyronia, Livaniou, Evangelia, Cumbes, Bevan, Lai, F. Anthony, George, Christopher H., Swann, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195308/ https://www.ncbi.nlm.nih.gov/pubmed/21692749 http://dx.doi.org/10.1042/BJ20101581 |
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