Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA

[Image: see text] A furan amino acid, inspired by the recently discovered proximicin natural products, was incorporated into the scaffold of a DNA-binding hairpin polyamide. While unpaired oligomers of 2,4-disubstituted furan amino acids show poor DNA-binding activity, furan (Fn) carboxamides paired...

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Detalles Bibliográficos
Autores principales: Muzikar, Katy A., Meier, Jordan L., Gubler, Daniel A., Raskatov, Jevgenij A., Dervan, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195311/
https://www.ncbi.nlm.nih.gov/pubmed/21957930
http://dx.doi.org/10.1021/ol202285y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195311/
https://www.ncbi.nlm.nih.gov/pubmed/21957930
http://dx.doi.org/10.1021/ol202285y

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