Cargando…
Expanding the Repertoire of Natural Product-Inspired Ring Pairs for Molecular Recognition of DNA
[Image: see text] A furan amino acid, inspired by the recently discovered proximicin natural products, was incorporated into the scaffold of a DNA-binding hairpin polyamide. While unpaired oligomers of 2,4-disubstituted furan amino acids show poor DNA-binding activity, furan (Fn) carboxamides paired...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2011
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195311/ https://www.ncbi.nlm.nih.gov/pubmed/21957930 http://dx.doi.org/10.1021/ol202285y |