Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene

Surgical resection was performed on a 47-year-old woman for a retroperitoneal mass that weighed 8.5 kg. Histological examination revealed a myxoid sarcomatous tumor. Because diagnosis could not be determined by immunohistochemistry, attention was focused on MDM2 (murine double minute) gene amplifica...

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Autores principales: Naiki, Taku, Hamamoto, Shuzo, Kawai, Noriyasu, Naiki-Ito, Aya, Kojima, Yoshiyuki, Yasui, Takahiro, Tozawa, Keiichi, Kohri, Kenjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195365/
https://www.ncbi.nlm.nih.gov/pubmed/22084793
http://dx.doi.org/10.5402/2011/261735
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author Naiki, Taku
Hamamoto, Shuzo
Kawai, Noriyasu
Naiki-Ito, Aya
Kojima, Yoshiyuki
Yasui, Takahiro
Tozawa, Keiichi
Kohri, Kenjiro
author_facet Naiki, Taku
Hamamoto, Shuzo
Kawai, Noriyasu
Naiki-Ito, Aya
Kojima, Yoshiyuki
Yasui, Takahiro
Tozawa, Keiichi
Kohri, Kenjiro
author_sort Naiki, Taku
collection PubMed
description Surgical resection was performed on a 47-year-old woman for a retroperitoneal mass that weighed 8.5 kg. Histological examination revealed a myxoid sarcomatous tumor. Because diagnosis could not be determined by immunohistochemistry, attention was focused on MDM2 (murine double minute) gene amplification by fluorescence in situ hybridization (FISH) analysis. The tumor was finally determined to be a dedifferentiated liposarcoma. We experienced a case of a giant retroperitoneal dedifferentiated liposarcoma. FISH analysis was useful for the diagnosis and determination of the therapeutic strategy.
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spelling pubmed-31953652011-11-14 Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene Naiki, Taku Hamamoto, Shuzo Kawai, Noriyasu Naiki-Ito, Aya Kojima, Yoshiyuki Yasui, Takahiro Tozawa, Keiichi Kohri, Kenjiro ISRN Urol Case Report Surgical resection was performed on a 47-year-old woman for a retroperitoneal mass that weighed 8.5 kg. Histological examination revealed a myxoid sarcomatous tumor. Because diagnosis could not be determined by immunohistochemistry, attention was focused on MDM2 (murine double minute) gene amplification by fluorescence in situ hybridization (FISH) analysis. The tumor was finally determined to be a dedifferentiated liposarcoma. We experienced a case of a giant retroperitoneal dedifferentiated liposarcoma. FISH analysis was useful for the diagnosis and determination of the therapeutic strategy. International Scholarly Research Network 2011 2011-06-16 /pmc/articles/PMC3195365/ /pubmed/22084793 http://dx.doi.org/10.5402/2011/261735 Text en Copyright © 2011 Taku Naiki et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Naiki, Taku
Hamamoto, Shuzo
Kawai, Noriyasu
Naiki-Ito, Aya
Kojima, Yoshiyuki
Yasui, Takahiro
Tozawa, Keiichi
Kohri, Kenjiro
Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title_full Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title_fullStr Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title_full_unstemmed Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title_short Giant Retroperitoneal Mucinous Tumor Supportively Diagnosed as a Dedifferentiated Liposarcoma by Fluorescence In Situ Hybridization of MDM2 Gene
title_sort giant retroperitoneal mucinous tumor supportively diagnosed as a dedifferentiated liposarcoma by fluorescence in situ hybridization of mdm2 gene
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195365/
https://www.ncbi.nlm.nih.gov/pubmed/22084793
http://dx.doi.org/10.5402/2011/261735
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